Group: Syria blasts kill, wound dozens of troops

International Space Station supply ship takes off from Kazakhstan - video

explosions of Russian spacecraft Progress 49 supply off from the Baikonur Cosmodrome in the Kazakh steppe desert

Police investigate Michael Mates election fraud allegation

rival candidate for Hampshire police commissioner since former Conservative minister accused of misrepresenting their residence

Thames Valley Police are interviewing witnesses about credits a former Conservative minister misrepresented their place of permanent residence for the election next week, Police Commissioner Hampshire.

The former Northern Ireland Minister Michael Mates (below), denied the allegations of fraud made by a rival candidate in the race for the £ 85 charge .000 year, but the police should ask witnesses before voters go to the polls on November 15.

Under the rules of the police and crime commissioner election, candidates must be registered to vote in local elections in the region who want to stay in "both at the time of [his] presentation appointment and election day. "

former lawyer Don Jerrard, presented as the representative of the Party of Justice and the fight against corruption said Mates, East Hampshire MP for 36 years, until 2010, had entered an apartment building in Winchester as a residence.

Jerrard said he had spent the fraud charges Mates Hampshire police chief believe that until recently included on electoral lists in neighboring West Sussex, where he lived with his wife since 15 years.

• The complaint was filed with the police Hampshire, but the investigation is held by Thames Valley Police to avoid any conflict of interest with the strength that candidates are hoping to become Commissioner.

Mates In September called the local association of their own party to resign as commissioner candidate after allegations of irregularities prior approval of the Central London property financed by members' expenses.

Speaking to BBC Radio Solent Mates on Friday said he was aware of the law and asked the advice of his agent that the selection process had started, even on housing Rental to provide a residential address.

"I lived outside Hampshire 500 meters for the past 15 years," he said. "I could apply to Sussex, but my heart is in Hampshire, my service is in Hampshire. "

"The electoral office in Winchester is happy ... and I have my certificate. Such is the returning officer at Southampton."

"I was a local person from Hampshire in the past 38 years," he added.

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Survivors, captain hear Italian shipwreck evidence

Officials: Turkey retaliates to Syrian shelling

Authorities say Turkish troops crossed the border into Syria bombing avenged for the sixth day.

Why Bring Up the Bodies should win the 2012 Booker Prize - video

Paul Laity said Hilary Mantel expected to win a second Booker Prize for bringing members

Paul Laity

Richard Sprenger

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J.K. Rowling's daughter 'tutored' her on teen slang

Strike enforced in Bangladesh over anti-Islam film

schools and businesses are closed and transport was disrupted by Bangladesh as a hard-line Islamic groups protest a film that denigrates the Prophet Muhammad answer general strike.


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Pope makes peace appeal at open-air Mass in Beirut

Russia's Medvedev plays down split with West on Syria

Syria's rebels fear foreign jihadis in their midst

As Salafists seek to achieve final battle against the Shiites, an ancient village said: "They call to the seventh century '

early summer, Abu Ismail, a veteran of six seasons of al-Qaida, to the left of the insurgency still burns in his native Iraq and went to he believes to be the beginning of the Apocalypse.

guaranteed cash benefactor in northern Iraq Erbil, then went to an arms dealer in Anbar province, a desolate corner of the country that no longer one breakpoint for jihadists from Syria and now is a gateway for those going in the opposite direction.

"It was easy," he said in the living room of a house in the Syrian city of Aleppo. "The money was not a problem, nor the weapon, or motivation. It will be a great fight against the enemy. "

Around

tanned 23 years, had three members of a Syrian rebel militia acting as your hosts. They looked at the floor as a young jihadist explained Quranic teachings were said to shape the coming battle. "Whatever the future," he said. "I care about today. Muhammad is the Messenger says there will be a battle between the Persians and the Sunni. And to come.

"When the regime falls, all those who fought against Muslims will be my enemy, particularly the Shiites," he said, reiterating a view shared by some extremist Sunnis that Shiites are their greatest enemies.

hosts trembling, avoiding eye contact. The stranger in their midst had sought refuge among them two months ago. Since then had rented a house, won a trip to the combat zone when he wants and has won the support of some of the rebel units in the region.

Even won a coveted award:. The right to marry the daughter of a cousin of the fighter, a union which took place on Thursday with the blessing of qualified residents and clerics

Not everyone in the unit was happy with the marriage. "Are you scratch my back, I'll scratch yours," said a young rebel, Abu Saif. "It is a Salafist, no doubt about it," he added, referring to the ultra-fundamentalist school of thought Koran. "And it is not what we believe."

discuss with the uncle of the girl without a name, a young man who was sitting nearby, Abu Saif said. "Tell me what are the benefits we derive from it, or that your family receives" The guy shrugged without giving an answer.

As Syrian civil war grinds inexorably become so much a clash of ideologies as a military battle of wills. The first lines were hastily carved ancient stone heart of Aleppo and the suburbs of concrete during sunny summer days, now seems almost secondary in the contest to determine the kind of society that will one day stand on ruins.

For the most part, the opposition remains faithful to the spirit that has led to many cities and citizens to use control state President Bashar al-Assad on their lives. But around the periphery, there are indications that the original values ??of the revolution began to unravel. The story of a street facing a difficult condition drastically, so simple in March 2011, is now much more complicated.

"We got exactly what Tunisia and Egypt," said Mahmoud Razak, a trader in the suburbs. "The freedom and the opportunity to progress in life. But we thought that it would take 19 days as it did [in Egypt]. Now, 19 months. Knew it would not be too hard. "

For those who now hosts Abu Ismael, the Iraqi jihadist embodies one of the main problems. While men more conservative and pious in this part of Aleppo refuse to see the crisis that now consumes Syria in existential terms. For them, it is always a struggle for self-determination, not a place of confrontation with an enemy apocalyptic predestined.

"What the global jihad is this?" asked an old city, Abu Abdallah, after Iraq had failed to prepare their wedding. "We will use them as toys and Sunni communities were in Iraq. When they had their way with us will be required to return to the seventh century, under the blade of a sword."

• Abu Ismael has not hidden his desire to Syria to be at the heart of a renewed al-Qaida directed. In addition, exceptionally, hiding what he did in Iraq, or what he wanted to do in the new war. In a frank discussion about an hour, offered a rare glimpse into the design of the terrorist group in Syria and packed battle to assert the organization. "I was a member of the 2005-11 al-Qaeda," he said, his dark eyes in a steady gaze. "I joined with my father when I was 16 years old and apart from a and a half months in prison, I was very active in all directions. "

Iraqi girl's dress and behavior are clearly those of a Salafist. He refused to cigarettes, handcuffed in the back of his uniform at the ankle and wore a black hat on black hair very short. More informative, spoke with contempt of Shiite Muslims, who were increasingly he said travel to Syria to fight the Sunni opposition.

"They say they will protect Zeinab Mosque in Damascus Sit," he said in a shrine revered by Shiites. "The Jaish al-Mahdi [Mahdi Army] and Hezbollah just use it to cover the rest into Syria. We will not let them. Let the attack, perhaps not to destroy, but to fulfill them.

"There are about 50 Iraqis in every region of northern Syria. Maybe more. Is not it hard to get here, and it is difficult to find another mujahideen. We can fight where we want and when I want. Y God willing we will prevail. "
agitated Your hosts were not so sure. Bound by social mores that provide shelter and hospitality walkers, the rebel unit seemed to realize that the problems brewing between them and the global jihadist group growing. Numerous rebel groups The Guardian spoke this week, said a looming confrontation with newcomers.

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The inexorable rise of open access scientific publishing | Stephen Curry

A new study shows that the increase in open access publishing of research is faster than had been done before

Read:. Academic Edition is changing faster than anyone realized, according to a new study reported today in the journal BMC Medicine

Before 2000, the vast majority of research articles published in journals that can be read by academics they - or their university libraries - paid subscription. However, since the turn of the millennium, the growth of the World Wide Web has been accompanied by the emergence of open access publishing, if the search is made freely available online. According to results released today by Laasko and Björk, more than half of the research articles * may be freely available.

Game

academic publishing has changed irrevocably.

The change does not mean that scholars have adopted the free-for-all mentality that file sharing is the bug bear of the music industry. Instead, it reflects the spirit of deep amateur scholars, who have always seen the work of production and discuss the results of the research as part of the task.

While the dissemination of this research was based on the printing and distribution of scholarly journals, the subscription model editors was a sensible way to manage this business. But the possibilities offered by the web to the instantaneous distribution merged with the principle that publicly funded research should be freely available and promoted open access movement to the forefront of academic publishing. Flight physical limitations of the print edition should also help us understand the value of much more profitable in the central part of the research enterprise.

Improvement of open access has been hampered by opposition from some publishers who see a threat to a lucrative subscription model, and some sectors of the community researchers fear cast by overboard a set process in journals known. Scientists may have invented the Internet, but some remain suspicious of his character and detrimental to browse.

others, like me, are more optimistic about the promise of open access, as did the British government. In July this year, the Minister of Science David Willetts has warmly welcomed the report of the working group chaired by Dame Janet Finch on how to increase access to public research. The Government believes that open access as a means to accelerate the free distribution of scientific results, not only for researchers but also for companies that want to innovate new technologies, and as a necessary mechanism for the development of new text based computer methods and data mining to examine research results with a width and depth that no individual could hope to match.

Finch

recommendations are implemented as policy Research Councils UK, the body that oversees public spending on science and the humanities. In a bold move, the UK is committed to ensure that from April 2013, all research is funded by the State free of charge to readers.

policy is not without its critics, many of whom are concerned about the financial implications, since the new policy has a strong preference to facilitate open access publishers charge by paying "processing Item" ( APC) to ensure that the paper is available free on the publication (or access openly). The cost estimates are uncertain, but may be as high as £ 60m per year, which will come from the budget of the research, a sensitive point with researchers in these times of austerity.

A road less green is also available, if the author generally file a simplified version of the document in a repository without incurring the university by a publisher, but it remains to be seen whether it will be adopted in practice. Universities and research institutes are only beginning to find ways to implement the new policy (recently clarified by the RCUK).

They should be encouraged to explore Björk Laasko who, precisely, is published in an open access journal. Finnish researchers have found not only that nearly 17% of the research in the world are published in open access journals, a figure that is two to three times higher than previously thought, but that the exponential increase in open access publications shows no sign of slowing down.

the UK, with about 35% of the items should be available in the repositories by bank transfer - Parkway - the total percentage of documents open access (52% *) seems to have crossed the halfway mark.

Whatever the difficulties that universities and researchers may encounter in implementing the new RCUK policy, it is clear that there is no turning back. We look forward to a future in which there is free access to research results, both for researchers, businesses and the general public. The only question now is what can we do?

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iCancer: closing the net around cancer by getting the public involved | Stephen Curry

iCancer campaign used social media to raise funds for a Swedish laboratory to develop its new therapy, but it raises important questions about public participation in funding decisions

How should the public be involved in the decision to fund scientific research? Directly, this is the answer that offers a new campaign that aims to harness the power of social media to develop a treatment for cancer.

iCancer The campaign, created by the author Alexander Masters, aims to raise funds from the public for research on a new treatment for neuroendocrine tumors (NET) - The body of the gland cancer that release hormones under control of the nervous system. NET are difficult to treat because patients often have symptoms only after the cancer has reached a relatively late stage and began to spread to other parts of the body. Cancer that killed Steve Jobs, the charismatic founder and visionary of Apple, a year ago.

campaign not starting from scratch as a new type of therapy for NET is currently being developed in the laboratory of Professor Magnus Essand. iCancer specific objective is to help Swedish scientists go beyond what has hitherto been an insurmountable obstacle: the increase of £ 2m needed for clinical trials in human patients

In a multiple approach would surely win the admiration of Apple design chief Jonathan Ive research group Essand adenovirus intelligently redesigned itself a disease agent in the therapy. Your modified virus that normally causes colds, suggests rather NET cells for destruction.

litany of tricks design is impressive. Swedish researchers modified the surface of the virus particle to help drag beyond the patient's immune system and improve their ability to find and infect tumor cells. Other genetic changes suppressed viral replication in tumor cells and reproduction increased in tumor cells. Adenovirus infection disrupts tumor cells, a strategy to kill with a double whammy because the content published dead cells stimulate the immune system to bind to tumor cells.

Essand

modified virus was successful in mice, but is now dormant in your laboratory freezer for lack of funds to begin clinical trials.

This is where the Masters Author Alexander discovered. When he learned that his friend and publisher of Dido Davies had been diagnosed with the disease, control drag the Internet for information on networks and eventually found its way to the laboratory of Professor Essand. Horrified that promising therapy has been hampered by the lack of a relatively small amount of money, joined with friends and another patient, Dominic Nutt NET to launch a campaign on the Internet, hosted on iCancer.org.uk Essand provide the money needed to perform the first clinical trials on the safety and efficacy of viral therapy.

• is a bold ambition and commendable. But the journey a successful experience in a university laboratory for therapy practice is long and costly. As highlighted in the Economist Mariana Mazzucato
• state enterprise
• , private companies and venture capital firms are often reluctant to invest in technologies that n ' not have a clear path to a profitable product, preferring public sector to bear the risk of early stage of development. Most countries, the United Kingdom, including total lack of effective mechanisms for interim financing necessary to obtain a science lab up with investors. A particular problem is that the adenovirus Essand Swedish government does not fund human clinical trials.

campaign approach to solve this problem raises interesting questions at the interface between public research and scientific. Undoubtedly, it is mixed interest in the mechanisms of cancer research, and even stimulate dialogue, because the public is paying directly and may be more motivated to follow the results.

But how campaign sit with existing mechanisms for funding such research? Should be a free-for-all, with a building campaigns more organized and earn money? In Britain, cancer research is largely funded by the research councils and the charity Cancer Research UK. Funding mechanisms have the advantage that several applications are discussed in detail by scientific experts before taking decisions on how to allocate grants. Thus, a broader view can be taken and determine priorities with a certain detachment. But of course, the public is excluded.

iCancer approach appealed to the public, but despite the scientific arguments presented clearly and without hyperbole on the campaign website, do not necessarily have the details of a finance committee large field application required.

Where is the balance? E-mail exchange and my reading of the literature, it is clear that sniper Essand the teacher, but has used this funding mechanism for the extraordinary absence of an alternative mechanism for fundraising this scale clinical trials. The organizers obvious passion and the fate of patients with human sympathy call NET base. Who does not want the campaign to be a success?
Some of my learned colleagues preservatives may nod to the output of "protocol", but the experimenter in me a great interest in the campaign to achieve its objectives, the curiosity to see how they can disrupt funding landscape and the relationship between scientists and the general public. The organizers are also experimenting and discovering. The campaign is realistic about the prospects for success of the experimental therapy - is far from a given - but it also has a charming innocence.

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Blaine goes for shock-factor with latest stunt

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